Christian McCaffrey has been a key player on the San Francisco 49ers' offense this season. They are currently placed third in the NFC West behind the Seahawks and the Rams with a 9-4 record, competing for a spot in the playoffs. Kyle Shanahan and his team are scheduled to take on the Tennessee Titans in Week 15.

The main injury here is that the Saints will be without top running back Alvin Kamara once again. The veteran is out with knee and ankle injuries in this divisional clash with the Panthers, who can take first place in the NFC South with a win thanks to Tampa Bay's loss on Thursday.

The Dallas Cowboys receiver was injured during last week's loss to the Detroit Lions when he went up for a deep pass in the end zone and was contorting his body trying to make a one-handed catch. He couldn't make the catch and then landed hard and his head slammed on the ground.

Christian McCaffrey is still one of the 49ers' best operators.