The Carolina Panthers moved into first place in the NFC South when the Buccaneers lost on Thursday night, and Week 15 will see several more games that impact the playoff race.

When we look back at the 2025 regular season, we may be pointing to Week 14 as the pivotal moment that sculpted the playoff picture .

The Chargers are the No. 5 seed because Denver leads the AFC West. A Chargers victory would all but eliminate Kansas City, vanquishing Andy Reid from the playoffs and bringing fresh blood. An AFC North title, coupled with the Chargers continuing to win, would set up another Harbaugh Bowl, this time in the Wild Card round.

The Texans can lose up to two games and still make the playoffs. Winning the AFC South for the third straight season? It's much more complicated.

Broncos, Patriots, Jaguars, Steelers lead AFC; Rams, Packers, Seahawks top NFC with wild-card races tightening.

Over at DraftKings, the Jaguars are -165 to win the division, while the Texans are +150 and the Colts are +2200. And as of this writing, our friends at Sportsline give the Jaguars a 47% chance to win the division, while the Texans have a 34% chance and the Colts are down at 17%.

Here's an early look at predictions and picks to win the AFC, NFC and which team will be the Super Bowl 60 champion.

There are still seven available playoff spots in each of the AFC and NFC, but that could change as we enter Week 15 of the NFL season.