SANTA CLARA, Calif. — Never mind revenge. The 49ers are still trying to get over a massive Super Bowl hangover. Leave it to Patrick Mahomes and the Kansas City Chiefs to remind them of the task.

SEATTLE — His beanie could have been a crown. You should have seen Trent Williams after the San Francisco 49ers’ last game, wearing a winter hat with chunky crystals lining the bill.

The Dallas Cowboys (3-4) mounted a fourth-quarter comeback against the San Francisco 49ers (4-4) that gave them the football down six with three minutes left in the game, but they were unable to ...

San Franciscco 49ers head coach Kyle Shanahan revealed that star receiver Deebo Samuel Sr. is currently hospitalized with pneumonia and fluid in his lungs after trying to play against the Kansas ...

The San Francisco 49ers at the moment have +1000 odds of winning the Super Bowl. In their most recent game, the 49ers defeated the Tampa Bay Buccaneers 23-20. Brock Purdy had 353 yards on 25-of-36 ...

Just like last year, the San Francisco 49ers are spinning with some October funk. A year ago, Kyle Shanahan’s team took a three-game losing streak into a Week 9 bye, then came back to rip off a ...

The San Francisco 49ers suffered a huge loss Week 7 against the Kansas City Chiefs, losing top wide receiver Brandon Aiyuk for the remainder of the season. The 49ers later confirmed that Aiyuk ...

SANTA CLARA, Calif. — Malik Mustapha, the 49ers’ impressive rookie safety, was one of the bright spots in San Francisco’s 28-18 loss Sunday at Levi’s Stadium. He was aggressive in his ...

Ricky Pearsall is close to making his NFL debut. In fact, the San Francisco 49ers wide receiver could take the field for the first time very soon — as in this weekend, less than two months after ...