While both US and European-domiciled funds fully replicate the index, the Canadian fund invests its assets in its US-listed counterpart Vanguard S&P 500 ETF in place of individual stocks.
This fund and Primecap Odyssey Aggressive Growth POAGX focus on firms with rapid earnings growth potential, though the latter holds more small caps; Vanguard Primecap VPMCX and Primecap Odyssey ...