FANCJ promotes DNA synthesis through G-quadruplex structures.
vanderbilt.edu
FANCJ promotes DNA synthesis through G-quadruplex structures.
Our genome contains many G-rich sequences, which have the propensity to fold into stable secondary DNA structures called G4 or G-quadruplex structures. These structures have been implicated in cellular processes such as gene regulation and telomere maintenance. However, G4 sequences are prone to mutations particularly upon replication stress or ...
May 31, 2018
G-quadruplex DNA
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